Discussing study limitations in reports of biomedical studies – the need for more transparency (commentary)
This commentary addresses the problem of limited discussion of study limitations in biomedical research papers. The authors present …
Underreporting (of negative results) is not only found in commercially sponsored trials, but also in non-commercial research. At least some results of around half of all registered trials is published. Underreporting affects large and small trials, in early and in late phase trials. This matters because participants assume that they contribute to the advancement of medical knowledge and the evidence base for clinical decisions is distorted. The authors name some things that can and should be done. Registration of trials makes identification of underreported trials possible. The authors invite readers to sign the petition at alltrials.net.
Title: All trials must be registered and the results published
Authors: Chalmers I, Glasziou P, Godlee F
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